【あさの設え#３】胃もたれ「異常なし」の機能性ディスペプシアの奥に迫る！

機能性ディスペプシア（FD）の最新知見をNEJM論文から解説。内視鏡で異常なしでも続く胃もたれ・早期満腹感の原因は十二指腸の微小炎症だった？三環系抗うつ薬、六君子湯、半夏瀉心湯、鍼灸まで、西洋医学と東洋医学の治療を総まとめ。

参考文献

1. Pasricha PJ, Talley NJ. Functional Dyspepsia. N Engl J Med. 2026;394:166-76. doi:10.1056/NEJMcp2501860.
2. Kim K, Ko SJ, Cho SH, Kim J, Park JW. Efficacy and safety of Banxia Xiexin decoction for functional dyspepsia: A systematic review and meta-analysis. Front Pharmacol. 2023;14:1130257. doi:10.3389/fphar.2023.1130257.
3. Ko SJ, Park J, Kim MJ, Kim J, Park JW. Rikkunshito for functional dyspepsia: A systematic review and meta-analysis. J Gastroenterol Hepatol. 2021;36(1):64-74. doi:10.1111/jgh.15208.
4. Burns GL, Bruce JK, Minahan K, et al. Type 2 and type 17 immune cell profiles differ in functional dyspepsia. Front Immunol. 2023;13:1051632. doi:10.3389/fimmu.2022.1051632.
5. Xu Z, Zhang X, Shi H, Liang M, Ning F, Wang Q, Jia H. Acupuncture for psychological symptoms in functional dyspepsia: A systematic review and meta-analysis. PLoS One. 2024;19(3):e0298438. doi:10.1371/journal.pone.0298438.
6. Zhang J, Liu Y, Huang X, Chen Y, Hu L, Lan K, Yu H. Acupuncture for functional dyspepsia: A network meta-analysis. Evid Based Complement Alternat Med. 2020;2020:3872919. doi:10.1155/2020/3872919.
7. Kwon CY, Ko SJ, Lee B, Cha JM, Yoon JY, Park JW. Acupuncture as an add-on treatment for functional dyspepsia: A systematic review and meta-analysis. Front Med (Lausanne). 2021;8:682783. doi:10.3389/fmed.2021.682783.